In the modern world, there are many types of drugs on Tadalafil basis used to treat erectile dysfunction (ED).
ED – is an unpleasant condition when a man is not able to have an active sex life because of a weak erection during sexual intercourse.
This problem is common among elderly men or it can be a sign of an underlying health condition that needs immediate treatment.
Fortunately, nowadays there are a great number of treatment options that can cope with this disease.
Tadalafil: Drug Information
This is one of the most popular drugs for erectile disorders all over the world, and Australia is not an exception.
This medicine, called phosphodiesterase-5 inhibitors, stimulates blood flow to the penis and helps men get a firm erection.
Tadalafil has a mild, safe effect on the body, and a prolonged half-life, which means that one pill is more than enough to provide an effective and firm erection for 24-36 hours.
The pharmacokinetic properties of the medicine are not affected by food or alcohol.
It means that food does not have any influence on the rate and extent of absorption, and there are no restrictions regarding alcohol intake during the treatment.
According to the statistics, Tadalafil becomes more popular every month.
This drug is gaining on Viagra, especially in Australia and other countries outside the US market.
Recently, there have been some attempts to treat women with this medicine, but in this regard, the drug has not been studied enough.
When and How to Use it?
Currently, drugs with Tadalafil are used to cure the following diseases:
- pulmonary hypertension (increased blood pressure of the lungs);
- benign prostatic hyperplasia (prostate enlargement);
- erectile dysfunction (impotence).
Originally, it was created to cope with pulmonary hypertension.
Recent studies have shown that this medicine really facilitates the patient’s condition.
However, the drug does not eliminate the risk of a lethal outcome.
Drugs containing Tadalafil are used in the treatment of benign prostatic hyperplasia.
This disease is characterized by such symptoms as frequent urination, weak urine pressure, frequent night urination, incomplete bladder emptying, etc.
However, Tadalafil cannot be combined with alpha blockers.
This can cause severe complications, such as a dangerous drop in blood pressure.
Drugs containing Tadalafil, cannot be combined with nitrate-containing drugs.
That’s why this preparation is more effective to treat ED.
The drug helps to overcome any degree of impotence.
As already mentioned, the effect of Tadalafil has not been studied enough on women.
Therefore, drugs with Tadalafil are recommended only for men.
Tadalafil drugs can be taken one-time or daily.
With daily use, a dosage of 5 mg is used.
The dose can be increased to 10 mg or decreased to 2.5 mg depending on the complexity of the disease and patient condition.
Cialis works within 30 minutes from ingestion and its effect can last from eight to 36 hours.
Tadalafil guarantees a stable erection for prolonged sexual intercourse.
After the implementation of an ejaculation, Cialis stimulates the body for a speedy recovery to continue sexual contact.
The medicine can be taken before, during or after a meal. Tadalafil-containing drugs do not become less effective because of the high or low amount of fats in foods.
Bear in mind!
You should consult with your doctor and disclose all health issues you have and medications you take before Cialis treatment in order to avoid severe adverse effects and any other complications.
The drug is well tolerated by patients.
Most common side effects are headaches and dyspepsia (indigestion).
Tadalafil: The History of Creation
It’s not a secret that Viagra was the first drug that radically changed ideas about erectile disorders treatment.
Penis injections, vacuum pumps, and other invasive procedures were replaced by a highly effective drug.
But, in 2003 two new drugs to increase potency entered the pharmaceutical market – Cialis (tadalafil) and Levitra (vardenafil).
In 1993, the American International Pharmaceutical Corporation “AIKOS” began a full-scale study of phosphodiesterase-5 inhibitors.
As in the case of Viagra, the new drug was originally intended for the treatment of other diseases.
Only when the ability of Viagra to increase erection was announced, AIKOS Corporation decided to test it for this purpose.
The patent was obtained in 1994.
The second phase of clinical trials of the active substance Tadalafil began in 1997.
Drugs based on Tadalafil were approved in 2003.
Currently, Tadalafil is being produced under two brand names:
- Cialis – to cure erectile dysfunction;
- Adcirca – to cure pulmonary hypertension.